Production of Pharmaceutical Grade Hydrate

Hi Friends,

Here, we will discuss about specifications, production process route and applications of Pharmaceutical grade hydrate. 

Specialty grade of hydrated alumina used in formulation of pharmaceutical products are known as Pharmaceutical grade hydrate. Highest purity level particularly with respect to lowest level of alkali and fineness are the prime requirements in the product.

Product Specifications:

Typical quality specifications of Pharmaceutical grade hydrate are outlined below-

Al(OH)₃ : 99.5% min.

Al₂O₃: 64.0% min.

Fe₂O₃: 0.012% max.

SiO₂: 0.012% max.

Na₂O: 0.05% max.

Moisture: 0.40% max.

LOI at 1100^oC: 34.5%

Median particle size (d₅₀): 1 micron.

Production Process:

Pharmaceutical grade hydrate is produced using Chemical grade hydrate as the feed stock. The hydrate is ground in ceramic lined ball mill and ground hydrate is washed using very dilute acidic water (acid not more than 1% in water) in order to minimize the alkali content in the product. The properly washed hydrate is dried and packed for despatch to destination.

Industrial Applications:

Major applications Pharmaceutical grade hydrate are listed below-

• Manufacture of toothpaste as hardness of hydrate is matching with the hardness of our tooth enamel,
• Medicinal application as Antacids.

Request to kindly put your views / suggestions / remarks / comments, if any.

Regards.

Kunwar Rajendra